Find out how Wegovy® pen for adults with obesity, or with overweight and at least one weight-related medical problem, along with a reduced-calorie diet and increased physical activity, can help you lose weight and keep it off.
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The results speak for themselves. Here's what the data says:
In a 72-week medical study of 1,407 adults living with obesity, along with a reduced-calorie diet and increased physical activity: Adults taking Wegovy® HD pen lost an average of 19% body weight (~47 lb) compared to people taking placebo (not on medicine) who lost 4% (~10 lb). 89% of adults taking Wegovy® HD lost 5% or more weight compared with 38% taking placebo.
See Wegovy® HD pen study details here.
Curious about your potential weight loss with Wegovy® HD pen?
Calculate it here.
In the same study
31% of adults taking Wegovy® HD lost 25% or more weight compared with 0% of adults on placebo.
Individual results may vary.
Wegovy® HD study details
Results are from a 72-week medical study of 1,407 adults with obesity (BMI ≥30 kg/m2). Adults with type 2 diabetes were excluded. Patients were taking either Wegovy® HD pen, Wegovy® 2.4 mg pen, or placebo. All groups received instruction for a reduced-calorie diet and increased physical activity. During the trial, 12% of participants taking Wegovy® HD discontinued treatment compared with 29% taking placebo.
BMI=body mass index.
Weight loss results with Wegovy® 2.4 mg pen
In a 68-week medical study of 1,961 adults with obesity, or with overweight and at least one weight-related medical problem, along with a reduced-calorie diet and increased physical activity:
Adults who used Wegovy® 2.4 mg pen achieved on average 15% weight loss
Adults who took placebo achieved on average ~2.5% weight loss (~6 lb) based on a 232 lb starting weight. 83% of adults using Wegovy® 2.4 mg pen lost 5% or more weight compared with 31% taking placebo.
Benefits beyond the scale
While not approved to treat these conditions, adults using Wegovy® 2.4 mg pen experienced improvements in:
WAIST SIZE
BLOOD PRESSURE
CHOLESTEROL
BLOOD SUGAR
Some adults using Wegovy® experienced an increase in resting heart rate.
Results are from a 68-week medical study of 1,961 adults with obesity (BMI ≥30 kg/m2), or with overweight (BMI ≥27 kg/m2) and at least one weight-related medical problem, including high blood pressure or high cholesterol. Adults with type 2 diabetes were excluded. Patients were taking either Wegovy® 2.4 mg pen or placebo. Both groups received instruction for a reduced-calorie diet and increased physical activity. During the trial, 17% of participants taking Wegovy® discontinued treatment compared with 22% taking placebo.
BMI=body mass index.
Learn more about Wegovy® pen for weight loss
Remember, if it’s not made by Novo Nordisk®, it’s not FDA-approved Wegovy®.
Your healthcare professional will determine the dose that's right for you and make any needed adjustments. Always follow the detailed instructions provided by your healthcare professional and in the Instructions for use, including specific timing and food considerations.
FDA=Food and Drug Administration.
FAQs about Wegovy® pen
With a maintenance dose of 2.4 mg: In a medical study, adults living with obesity, or with overweight and at least one weight-related medical problem, who used Wegovy® 2.4 mg pen, along with a reduced-calorie diet and increased physical activity, lost ~35 lb, or on average 15% of their starting body weight. In comparison, adults who used placebo lost ~6 lb, or on average about 2.5% of their body weight. The average starting weight for both groups was 232 lb.
83% or about 8 in 10 adults achieved 5% or more weight loss with Wegovy® 2.4 mg pen compared with 31% taking placebo.*
*Results are from a 68-week medical study of 1,961 adults with obesity (BMI ≥30 kg/m2), or with overweight (BMI ≥27 kg/m2) and at least one weight-related medical problem, including high blood pressure or high cholesterol. Adults with type 2 diabetes were excluded. Patients were taking either Wegovy® 2.4 mg pen or placebo. Both groups received instruction for a reduced-calorie diet and increased physical activity. During the trial, 17% of participants taking Wegovy® discontinued treatment compared with 22% taking placebo.
With a maintenance dose of Wegovy® HD (semaglutide) injection 7.2 mg: In a medical study, adults living with obesity who used Wegovy® 7.2 mg pen, along with a reduced-calorie diet and increased physical activity, lost ~47 lb, or on average 19% of their starting body weight. In comparison, adults who used placebo lost ~10 lb, or on average 4% of their body weight. The average starting weight for both groups was 248 lb.
About 1 in 3 adults achieved 25% or more weight loss, ~62 lb based on a 248 lb starting weight.†
†Results are from a 72-week medical study of 1,407 adults with obesity (BMI ≥30 kg/m2). Adults with type 2 diabetes were excluded. Patients were taking Wegovy® injection 7.2 mg, Wegovy® injection 2.4 mg, or placebo. All groups received instruction for a reduced-calorie diet and increased physical activity. During the trial, 12% of participants taking Wegovy® injection 7.2 mg discontinued treatment compared with 29% taking placebo.
BMI=body mass index.
People respond to medication, including Wegovy®, differently, so there is no set time when you can expect to see results with Wegovy®. Ask your healthcare professional about what might be realistic for you.
Wegovy® HD (7.2 mg) may be an option for adults who are looking to lose additional weight after being on the 2.4 mg dose for at least 4 weeks. Talk to your doctor about whether stepping up to a higher dose could be right for you.
Wegovy® HD is a higher dose of semaglutide, the same active ingredient that’s in the Wegovy® 2.4 mg pen. It is a single-dose pen, just like other Wegovy® once-weekly injections. Like all forms of Wegovy® (pill or pen), Wegovy® HD is used along with a reduced-calorie diet and increased physical activity to help you lose weight and keep it off.
The Wegovy® (semaglutide) pen is a prefilled, single-use pen used to deliver a once-weekly semaglutide injection for weight management. The pen contains a hidden needle and is preset with the prescribed dose. Patients should follow the Instructions for Use and guidance from their healthcare professional when administering Wegovy®.
Yes, unused Wegovy® pens should be stored in the refrigerator between 36 °F to 46 °F (2 °C to 8 °C). Wegovy® pens can also be kept at room temperature (46 °F to 86 °F) before removing the pen cap and in the original carton for up to 28 days.
If you miss a dose of your Wegovy® injection and there are more than 2 days until your next scheduled dose, take the missed dose as soon as you remember. If it's less than 2 days, skip the missed dose and take your next dose on the regularly scheduled day. If you miss doses of Wegovy® for 2 or more weeks, take your next dose on the regularly scheduled day or call your healthcare professional to talk about how to restart your treatment.
No, each Wegovy® pre-filled pen contains one dose of semaglutide and is designed for single use. It should be properly disposed of after each weekly injection.
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Wegovy® may cause serious side effects, including:
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Wegovy® may affect the way some medicines work and some medicines may affect the way Wegovy® works. Tell your healthcare provider if you are taking other medicines to treat diabetes, including sulfonylureas or insulin. Wegovy® slows stomach emptying and can affect medicines that need to pass through the stomach quickly.
Wegovy® may cause serious side effects, including:
The most common side effects of Wegovy® may include: nausea, diarrhea, vomiting, constipation, stomach (abdomen) pain, changes in skin sensations, headache, tiredness (fatigue), upset stomach, dizziness, feeling bloated, belching, low blood sugar in people with type 2 diabetes, gas, stomach flu, heartburn, and hair loss.
Please see Prescribing Information and Medication Guide for Wegovy®.
Wegovy® is a prescription medication.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
This site is intended for US patients only.
Wegovy® (semaglutide) injection and Wegovy® (semaglutide) tablets are prescription medicines used with a reduced calorie diet and increased physical activity to:
Wegovy® contains semaglutide and should not be used with other semaglutide-containing products or other GLP-1 receptor agonist medicines.
It is not known if Wegovy® injection is safe and effective:
It is not known if Wegovy® tablets are safe and effective for use in people under 18 years of age.
Wegovy® (semaglutide) injection and Wegovy® (semaglutide) tablets are prescription medicines used with a reduced calorie diet and increased physical activity to:
Wegovy® contains semaglutide and should not be used with other semaglutide-containing products or other GLP-1 receptor agonist medicines.
It is not known if Wegovy® injection is safe and effective:
It is not known if Wegovy® tablets are safe and effective for use in people under 18 years of age.
Wegovy® may cause serious side effects, including:
Wegovy® may cause serious side effects, including:
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Wegovy® may affect the way some medicines work and some medicines may affect the way Wegovy® works. Tell your healthcare provider if you are taking other medicines to treat diabetes, including sulfonylureas or insulin. Wegovy® slows stomach emptying and can affect medicines that need to pass through the stomach quickly.
Wegovy® may cause serious side effects, including:
The most common side effects of Wegovy® may include: nausea, diarrhea, vomiting, constipation, stomach (abdomen) pain, changes in skin sensations, headache, tiredness (fatigue), upset stomach, dizziness, feeling bloated, belching, low blood sugar in people with type 2 diabetes, gas, stomach flu, heartburn, and hair loss.
Please see Prescribing Information and Medication Guide for Wegovy®.
Wegovy® is a prescription medication.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
This site is intended for US patients only.
Wegovy® (semaglutide) injection and Wegovy® (semaglutide) tablets are prescription medicines used with a reduced calorie diet and increased physical activity to:
Wegovy® contains semaglutide and should not be used with other semaglutide-containing products or other GLP-1 receptor agonist medicines.
It is not known if Wegovy® injection is safe and effective:
It is not known if Wegovy® tablets are safe and effective for use in people under 18 years of age.